The Ventura operating system release for MAC available late 2022 made a change to installation of drivers for Prolific devices. This may affect use of those devices completely... but we don't have enough testing for that concluision yet. Right now, I want to talk about Yaesu's SCU cable series. The drivers for these cables will install only from the App store. This will get it done:
Remember, while the RT Systems programmers will work with the Yaesu cables, there are RT Systems cables that work and do not require installation of special drivers.